Obesity – Prevention and therapy
Obesity is a serious problem, particularly with regard to the associated concomitant diseases. The aim is to develop and scientifically test prevention and treatment concepts. Initially, the cooperative project "Interdisciplinary Therapy of Obesity and its Effects on Weight History, Quality of Life and Gastrointestinal Parameters (Subproject Obesity and GastroIntestinal Tract OGIT)" was funded by the BMBF.
LIBRE Study
Women with a germline mutation in the BRCA-1 or -2 gene have a high lifetime risk of breast or ovarian cancer. It is likely that exogenous factors, especially lifestyle factors such as exercise and diet, can modulate the risk of cancer. The randomized, prospective, multicenter intervention study in women with mutation in the BRCA1/2 gene (LIBRE study) investigates the effects of a structured lifestyle intervention program involving physical activity and Mediterranean diet. According to the study findings, the Mediterranean diet is associated with a lower risk of cancer. The cooperation project is coordinated by the Clinic for Gynecology and Obstetrics, University Hospital 'Klinikum rechts der Isar' of the Technical University Munich (TUM) and was initially funded by the German Cancer Aid.
Malnutrition / Artificial nutrition
Malnutrition also occurs in industrialized countries, especially in risk groups such as the very elderly, sick and socially weak. The loss of muscle mass (sarcopenia) plays a special role. The Metabolic Unit investigates concepts that are suitable for detecting, treating or preventing malnutrition. This includes the testing of dietary supplements, food additives and medical nutrition (enteral and parenteral), but also the development of guidelines and validation of supply concepts.
Microalgae- Bioavailability and Safety
A healthy diet is increasingly becoming a scientific and technical challenge. Microalgae are a possible answer to the threat of limited food resources, such as meat and fish. The composition of microalgae varies and includes omega-3 fatty acids, carotenoids and proteins, which may have potential physiological and preventive effects on human nutrition.The institute 180a is investigating in more detail the human intake of the microalgae Phaeodactylum tircornutum (PT) and its nutrient bioavailability and health benefits (gut health, inflammatory processes).
